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Impact on the Sustainable Development Goals (SDGs)

Analysis of institutional authors

Bartoli Duncan, Claudia AnnaAuthor

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November 29, 2024
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Radiation-Induced Rhinitis: Cytological and Olfactory Changes

Publicated to: American Journal Of Rhinology & Allergy. 33 (2): 153-161 - 2019-03-01 33(2), DOI: 10.1177/1945892418822448

Authors:

Riva, Giuseppe; Franco, Pierfrancesco; Provenzano, Erica; Arcadipane, Francesca; Bartoli, Claudia; Lava, Paolo; Ricardi, Umberto; Pecorari, Giancarlo
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Affiliations

AOU Citta Salute & Sci, Dept Oncol, Radiat Oncol, Turin, Italy - Author
Maria Vittoria Hosp, Otorhinolaryngol Div, Turin, Italy - Author
Univ Turin, Dept Oncol, Radiat Oncol, Turin, Italy - Author
Univ Turin, Dept Surg Sci, Otorhinolaryngol Div, Via Genova 3, I-10126 Turin, Italy - Author
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Abstract

Background Oral mucositis is a well-known adverse event of radiotherapy (RT) for head and neck cancer (HNC). Its nasal counterpart, the radiation-induced rhinitis, is poorly studied and considered in clinical practice. Objective The aim of this observational study was to evaluate acute cytological and olfactory alterations during RT and their correlation with RT doses. Methods Ten patients who underwent RT for HNC, excluding tumors of the nasal cavities, were evaluated with nasal scraping for cytological examination, Sniffin' Sticks test for olfactory assessment, and Nasal Obstruction Symptom Evaluation scale. The examinations were performed before (T0), at mid-course (T1), and at the end (T2) of RT. They were repeated 1 and 3 months after RT (T3 and T4). Mean dose (D-mean) and near maximum dose (D-2%) to nasal cavities and inferior turbinates were used for correlation analyses. Results Radiation-induced rhinitis was present in 70% of patients at T2, and it was still observed in 40% of cases after 3 months. Although olfactory function remained within the normal range at the evaluated times, a significant decrease in odor threshold and discrimination was observed during RT, which returned to baseline levels after RT. Nasal cytology showed a radiation-induced rhinitis with neutrophils and sometimes bacteria. Mucous and squamous cell metaplasia appeared in 10% of patients. D-mean and D-2% to inferior turbinates were associated to neutrophilic rhinitis at T2, and D-2% to inferior turbinates was correlated to mucous cell metaplasia at T2. Conclusions RT for HNC induces acute rhinitis that may persist after the completion of treatment and can affect patient's quality of life. Nasal cytology can help to choose the best treatment on an individual basis.
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Keywords

Peace, justice, and strong institutions

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal American Journal Of Rhinology & Allergy due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2019, it was in position 15/42, thus managing to position itself as a Q2 (Segundo Cuartil), in the category Otorhinolaryngology. Notably, the journal is positioned en el Cuartil Q2 para la agencia Scopus (SJR) en la categoría Otorhinolaryngology.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.8. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 13, 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-12-21, the following number of citations:

  • WoS: 21
  • Open Alex: 24
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-12-21:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 57.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 57 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 8.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Continuing with the social impact of the work, it is important to emphasize that, due to its content, it can be assigned to the area of interest of ODS 16 - Promote peaceful and inclusive societies for sustainable development, provide access to justice for all and build effective, accountable and inclusive institutions at all levels, with a probability of 62% according to the mBERT algorithm developed by Aurora University.
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Italy.

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