February 5, 2018
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Article

Aluminum Nanoholes for Optical Biosensing.

Publicated to: Biosensors. 5 (3): 417-431 - 2015-09-01 5(3), DOI: 10.3390/bios5030417

Authors:

Barrios, CA; Canalejas-Tejero, V; Herranz, S; Urraca, J; Moreno-Bondi, MC; Avella-Oliver, M; Maquieira, A; Puchades, R
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Affiliations

Grupo de Dispositivos Semiconductores del ISOM. Universidad Politécnica de Madrid - Author
Univ Complutense Madrid, Dept Quim Analit, Madrid 28040, Spain - Author
Univ Politecn Madrid, Dept Tecnologia Fotonica & Bioingn, ETSI Telecomun, Madrid 28040, Spain - Author
Univ Politecn Madrid, Inst Sist Optoelect Microtecnologia, ETSI Telecomun, Ciudad Univ S-N, Madrid 28040, Spain - Author
Univ Politecn Valencia, Inst Reconocimiento Mol & Desarollo Tecnol, Dept Quim, Valencia 46022, Spain - Author
UPM, UCM, Madrid 28040, Spain - Author
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Abstract

wavelength diameter holes in thin metal layers can exhibit remarkable optical features that make them highly suitable for (bio) sensing applications. Either as efficient light scattering centers for surface plasmon excitation or metal-clad optical waveguides, they are able to form strongly localized optical fields that can effectively interact with biomolecules and/or nanoparticles on the nanoscale. As the metal of choice, aluminum exhibits good optical and electrical properties, is easy to manufacture and process and, unlike gold and silver, its low cost makes it very promising for commercial applications. However, aluminum has been scarcely used for biosensing purposes due to corrosion and pitting issues. In this short review, we show our recent achievements on aluminum nanohole platforms for (bio) sensing. These include a method to circumvent aluminum degradation-which has been successfully applied to the demonstration of aluminum nanohole array (NHA) immunosensors based on both, glass and polycarbonate compact discs supports-the use of aluminum nanoholes operating as optical waveguides for synthesizing submicron-sized molecularly imprinted polymers by local photopolymerization, and a technique for fabricating transferable aluminum NHAs onto flexible pressure-sensitive adhesive tapes, which could facilitate the development of a wearable technology based on aluminum NHAs.
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Keywords

AluminumBiosensing techniquesMetal nanoholesMolecularly imprinted polymerNanohole arraysNanopatterningNanostructuresOptical biosensingPhotochemical processesPhotopolymerizationPolycarbonatePolycarboxylate cementSurface plasmon resonanceTransfer printing

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Biosensors due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2015, it was in position , thus managing to position itself as a Q2 (Segundo Cuartil), in the category Medicine (Miscellaneous).

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-26:

  • WoS: 14
  • Scopus: 17
  • Europe PMC: 4
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-26:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 46 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: https://oa.upm.es/40698/

As a result of the publication of the work in the institutional repository, statistical usage data has been obtained that reflects its impact. In terms of dissemination, we can state that, as of

  • Views: 401
  • Downloads: 250
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Chad.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Barrios CA) .

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Awards linked to the item

The authors gratefully acknowledge financial support from MINECO projects, Spain (TEC2012-31145, CTQ2012-37573-C02 and CTQ 2013-45875-R).
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