June 9, 2019
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Implementation and Performance of Automated Software for Computing Right-to-Left Ventricular Diameter Ratio From Computed Tomography Pulmonary Angiography Images

Publicated to: JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY. 40 (3): 387-392 - 2016-06-01 40(3), DOI: 10.1097/RCT.0000000000000375

Authors:

Kumamaru, KK; George, E; Aghayev, A; Saboo, SS; Khandelwal, A; Rodríguez-López, S; Cai, TR; Jiménez-Carretero, D; Estépar, RSJ; Ledesma-Carbayo, MJ; González, G; Rybicki, FJ
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Affiliations

Brigham & Womens Hosp, Dept Radiol, Appl Imaging Sci Lab, 75 Francis St, Boston, MA 02115 USA - Author
Brigham & Womens Hosp, Surg Planning Lab, 75 Francis St, Boston, MA 02115 USA - Author
CIBER BBN, Madrid, Spain - Author
Juntendo Univ, Dept Radiol, Tokyo, Japan - Author
MIT, Elect Res Lab, Madrid MIT Vis Consortium M, Cambridge, MA 02139 USA - Author
Ottawa Hosp, Dept Radiol, Ottawa, ON, Canada - Author
Univ Ottawa, Ottawa, ON, Canada - Author
Univ Politecn Madrid, Biomed Image Technol, Madrid, Spain - Author
Univ Texas SW Med Ctr Dallas, Dept Radiol, Dallas, TX 75390 USA - Author
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Abstract

Objective: The aim of this study was to prospectively test the performance and potential for clinical integration of software that automatically calculates the right-to-left ventricular (RV/LV) diameter ratio from computed tomography pulmonary angiography images. Methods: Using 115 computed tomography pulmonary angiography images that were positive for acute pulmonary embolism, we prospectively evaluated RV/LV ratio measurements that were obtained as follows: (1) completely manual measurement (reference standard), (2) completely automated measurement using the software, and (3 and 4) using a customized software interface that allowed 2 independent radiologists to manually adjust the automatically positioned calipers. Results: Automated measurements underestimated (P < 0.001) the reference standard (1.09 [0.25] vs 1.03 [0.35]). With manual correction of the automatically positioned calipers, the mean ratio became closer to the reference standard (1.06 [0.29] by read 1 and 1.07 [0.30] by read 2), and the correlation improved (r = 0.675 to 0.872 and 0.887). The mean time required for manual adjustment (37 [20] seconds) was significantly less than the time required to perform measurements entirely manually (100 [23] seconds). Conclusions: Automated CT RV/LV diameter ratio software shows promise for integration into the clinical workflow for patients with acute pulmonary embolism.
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Keywords

AlgorithmsComputed tomography angiographyComputer-aided detectionCtDeathDiameter ratioDysfunctionEchocardiographyEmbolismEnlargementHeart ventriclesHumansMachine learningMiddle agedMortalityObserver variationOrgan sizePattern recognition, automatedPredictorsPrognosisPulmonary arteryPulmonary embolismRadiographic image enhancementRadiographic image interpretation, computer-assistedReproducibility of resultsRight ventricular strainSensitivity and specificitySoftware

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2016, it was in position , thus managing to position itself as a Q2 (Segundo Cuartil), in the category Radiology, Nuclear Medicine and Imaging. Notably, the journal is positioned en el Cuartil Q3 for the agency WoS (JCR) in the category Radiology, Nuclear Medicine & Medical Imaging.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-24:

  • Google Scholar: 15
  • WoS: 6
  • Scopus: 9
  • Europe PMC: 3
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-24:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 41.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 42 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 4.
  • The number of mentions on the social network Facebook: 1 (Altmetric).
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: https://oa.upm.es/43630/

As a result of the publication of the work in the institutional repository, statistical usage data has been obtained that reflects its impact. In terms of dissemination, we can state that, as of

  • Views: 501
  • Downloads: 240
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Canada; Japan; United States of America.

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Awards linked to the item

Supported by the Comunidad de Madrid, Spain, through the Madrid-MIT M+Vision Consortium.
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