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Analysis of institutional authors

Bacete LAuthorMélida HAuthorLopez GAuthorMiedes EAuthorMolina ACorresponding Author

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May 12, 2020
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Arabidopsis response reGUlator 6 (ARR6) modulates plant cell-wall composition and disease resistance

Publicated to: MOLECULAR PLANT-MICROBE INTERACTIONS. 33 (5): 767-780 - 2020-05-01 33(5), DOI: 10.1094/MPMI-12-19-0341-R

Authors:

Bacete, Laura; Melida, Hugo; Lopez, Gemma; Dabos, Patrick; Tremousaygue, Dominique; Denance, Nicolas; Miedes, Eva; Bulone, Vincent; Goffner, Deborah; Molina, Antonio
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Affiliations

AlbaNova University Center - Author
Escuela Tecnica Superior de Ingenieros Agronomos de Madrid - Author
GEVES - Author
Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria - Author
Norges Teknisk-Naturvitenskapelige Universitet - Author
The University of Adelaide - Author
Univ Adelaide, Sch Agr Food & Wine, Waite Campus, Urrbrae - Author
Univ Paul Sabatier, Lab Rech Sci Vegetales, CNRS, UMR 5546, Chemin Borde Rouge - Author
Univ Politecn Madrid UPM, Ctr Biotecnol & Genom Plantas, Inst Nacl Invest & Tecnol Agr & Alimentaria INIA, Campus Montegancedo UPM, Pozuelo De Alarcon 28223 - Author
Univ Politecn Madrid, Dept Biotecnol Biol Vegetal, Escuela Tecn Super Ingn Agron Alimentaria & Biosi - Author
Univ Toulouse, INRA, UPS, CNRS,LIPM - Author
Universite Paul Sabatier Toulouse III - Author
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Abstract

© 2020 The American Phytopathological Society. The cytokinin signaling pathway, which is mediated by Arabidopsis response regulator (ARR) proteins, has been involved in the modulation of some disease-resistance responses. Here, we describe novel functions of ARR6 in the control of plant disease-resistance and cell-wall composition. Plants impaired in ARR6 function (arr6) were more resistant and susceptible, respectively, to the necrotrophic fungus Plectosphaerella cucumerina and to the vascular bacterium Ralstonia solanacearum, whereas Arabidopsis plants that overexpress ARR6 showed the opposite phenotypes, which further support a role of ARR6 in the modulation of disease-resistance responses against these pathogens. Transcriptomics and metabolomics analyses revealed that, in arr6 plants, canonical disease-resistance pathways, like those activated by defensive phytohormones, were not altered, whereas immune responses triggered by microbe-associated molecular patterns were slightly enhanced. Cell-wall composition of arr6 plants was found to be severely altered compared with that of wild-type plants. Remarkably, pectin-enriched cell-wall fractions extracted from arr6 walls triggered more intense immune responses than those activated by similar wall fractions from wild-type plants, suggesting that arr6 pectin fraction is enriched in wall-related damage-associated molecular patterns, which trigger immune responses. This work supports a novel function of ARR6 in the control of cell-wall composition and disease resistance and reinforces the role of the plant cell wall in the modulation of specific immune responses.
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Keywords

arabidopsis response regulators (arr)cell wallcytokinindamage-associated molecular patterns (damps)disease resistanceplectosphaerella cucumerinaralstonia solanacearumArabidopsisArabidopsis proteinsArabidopsis response regulators (arr)BiosynthesisCell wallConfers resistanceCytokininDamage-associated molecular patterns (damps)Defense responsesDisease resistanceExpressionGene expression regulation, plantHeterotrimeric g-proteinHumansImmunityPlant cellsPlant diseasesPlant immunityPlectosphaerella cucumerinaRalstonia solanacearumRalstonia-solanacearumReceptor-like kinaseSalicylic-acidStress

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal MOLECULAR PLANT-MICROBE INTERACTIONS due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2020, it was in position 37/235, thus managing to position itself as a Q1 (Primer Cuartil), in the category Plant Sciences.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.63. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 13, 2025)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 2.85 (source consulted: FECYT Mar 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2026-04-27, the following number of citations:

  • WoS: 44
  • Scopus: 45
  • Europe PMC: 11
  • Google Scholar: 39
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-27:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 94.

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 67.
  • The number of mentions on the social network Facebook: 1 (Altmetric).
  • The number of mentions on the social network X (formerly Twitter): 25 (Altmetric).
  • The number of mentions on Wikipedia: 1 (Altmetric).
  • The number of mentions in news outlets: 6 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: https://oa.upm.es/87514/

As a result of the publication of the work in the institutional repository, statistical usage data has been obtained that reflects its impact. In terms of dissemination, we can state that, as of

  • Views: 251
  • Downloads: 124
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Australia; France; Norway; Sweden.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (BACETE CANO, LAURA) and Last Author (MOLINA FERNANDEZ, ANTONIO).

the author responsible for correspondence tasks has been MOLINA FERNANDEZ, ANTONIO.

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