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Analysis of institutional authors

Sánchez‐parra BAuthorPérez‐alonso MmAuthorOrtiz‐garcía PAuthorMoya‐cuevas JAuthorPollmann SCorresponding Author

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March 19, 2021
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Accumulation of the auxin precursor indole‐3‐acetamide curtails growth through the repression of ribosome‐biogenesis and development‐related transcriptional networks

Publicated to: International Journal Of Molecular Sciences. 22 (4): 2040-21 - 2021-02-01 22(4), DOI: 10.3390/ijms22042040

Authors:

Sánchez-Parra, B; Pérez-Alonso, MM; Ortiz-García, P; Moya-Cuevas, J; Hentrich, M; Pollmann, S
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Affiliations

Escuela Tecnica Superior de Ingenieros Agronomos de Madrid - Author
Karl-Franzens-Universitat Graz - Author
Ruhr-Universitat Bochum - Author
Umea universitet - Author
Universidad Politécnica de Madrid - Author
‎ Karl Franzens Univ Graz, Inst Biol, Bereich Pflanzenwissensch, A-8010 Graz, Austria - Author
‎ Ruhr Univ Bochum, Lehrstuhl Pflanzenphysiol, D-44780 Bochum, Germany - Author
‎ Umea Univ, Umea Plant Sci Ctr, S-90736 Umea, Sweden - Author
‎ Univ Politecn Madrid UPM, Ctr Biotecnol & Genom Plantas, Inst Nacl Invest & Tecnol Agr & Alimentac INIA, Campus Montegancedo, Madrid 28223, Spain - Author
‎ Univ Politecn Madrid UPM, Dept Biotecnol Biol Vegetal, Escuela Tecn Super Ingn Agron Alimentaria & Biosi, Madrid 28040, Spain - Author
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Abstract

© 2021 by the authors. Licensee MDPI, Basel, Switzerland. The major auxin, indole‐3‐acetic acid (IAA), is associated with a plethora of growth and developmental processes including embryo development, expansion growth, cambial activity, and the induction of lateral root growth. Accumulation of the auxin precursor indole‐3‐acetamide (IAM) induces stress related processes by stimulating abscisic acid (ABA) biosynthesis. How IAM signaling is controlled is, at present, unclear. Here, we characterize the ami1 rooty double mutant, that we initially generated to study the metabolic and phenotypic consequences of a simultaneous genetic blockade of the indole glucosinolate and IAM pathways in Arabidopsis thaliana. Our mass spectro-metric analyses of the mutant revealed that the combination of the two mutations is not sufficient to fully prevent the conversion of IAM to IAA. The detected strong accumulation of IAM was, how-ever, recognized to substantially impair seed development. We further show by genome‐wide expression studies that the double mutant is broadly affected in its translational capacity, and that a small number of plant growth regulating transcriptional circuits are repressed by the high IAM content in the seed. In accordance with the previously described growth reduction in response to elevated IAM levels, our data support the hypothesis that IAM is a growth repressing counterpart to IAA.
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Keywords

ArabidopsisArabidopsis proteinsArabidopsis thalianaGene regulatory networksGerminationIndole glucosinolateIndole-3-acetamideIndole-3-acetic acidIndoleacetic acidsIndole‐3‐acetamideIndole‐3‐acetic acidMetabolic networks and pathwaysModels, molecularMutationOrganelle biogenesisPhenotypePlant growthProtein biosynthesisReproducibility of resultsRibosome biogenesisRibosomesSeed maturationSeed sizeSeedsTranscription, genetic

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal International Journal Of Molecular Sciences due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2021, it was in position 69/297, thus managing to position itself as a Q1 (Primer Cuartil), in the category Biochemistry & Molecular Biology.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-01-20:

  • WoS: 7
  • Scopus: 8
  • Europe PMC: 1
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-01-20:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 22.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 22 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 6.
  • The number of mentions on the social network X (formerly Twitter): 7 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Austria; Germany; Sweden.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (SANCHEZ PARRA, BEATRIZ) and Last Author (POLLMANN, STEPHAN).

the author responsible for correspondence tasks has been POLLMANN, STEPHAN.

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