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Analysis of institutional authors

Madrid-Garcia, AAuthor

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April 26, 2021
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Article

Influence of colchicine prescription in COVID-19-related hospital admissions: a survival analysis

Publicated to: Therapeutic Advances In Musculoskeletal Disease. 13 - 2021-03-01 13(), DOI: 10.1177/1759720X211002684

Authors:

Madrid-Garcia, Alfredo; Perez, Ines; Colomer, Jose Ignacio; Leon-Mateos, Leticia; Jover, Juan A.; Fernandez-Gutierrez, Benjamin; Abasolo-Alcazar, Lydia; Rodriguez-Rodriguez, Luis;
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Affiliations

Hosp Clin San Carlos, Dept Rheumatol, C Prof Martin Lagos S-N, Madrid 28040, Spain - Author
Hosp Clin San Carlos, Hlth Res Inst IdISSC, C Prof Martin Lagos S-N, Madrid 28040, Spain - Author
Univ Politecn Madrid, Escuela Tecn Super Ingn Telecomunicac ETSIT, Madrid, Spain - Author
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Abstract

Aims: To analyze the association between colchicine prescription and COVID-19-related hospital admissions in patients with rheumatic and musculoskeletal diseases (RMDs). Methods: Patients attending a rheumatology outpatient clinic from a tertiary care center in Madrid, Spain, from 1 September 2019 to 29 February 2020 were included. Patients were assigned as exposed or unexposed based on whether they were prescribed with colchicine in their last visit to the clinic during the 6 months before the start of the observation period. Treatment changes during the observation period were also considered. The primary outcome was COVID-19-related hospital admissions between 1 March and 20 May 2020. Secondary outcome included COVID-19-related mortality. Several weighting techniques for data balancing, based and non-based on the propensity score, followed by Cox regressions were performed to estimate the association of colchicine prescription on both outcomes. Discussion: The number of patients entered in the study was 9379, with 406 and 9002 exposed and unexposed follow-up periods, respectively. Generalized Boosted Models (GBMs) and Empirical Balancing Calibration Weighting (EBCW) methods showed the best balance for COVID-19-related hospital admissions. Colchicine prescription did not show a statistically significant association after covariable balancing (p-value = 0.195 and 0.059 for GBM and EBCW, respectively). Regarding mortality, the low number of events prevented a success variable balancing and analysis. Conclusion: Colchicine prescription does not play a significant protective or risk role in RMD patients regarding COVID-19-related hospital admissions. Our observations could support the maintenance of colchicine prescription in those patients already being treated, as it is not associated with a worse prognosis.
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Keywords

ColchicineCovid-19Hospital admissionSurvival analysisWeighting techniques

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Therapeutic Advances In Musculoskeletal Disease due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2021, it was in position , thus managing to position itself as a Q2 (Segundo Cuartil), in the category Orthopedics and Sports Medicine. Notably, the journal is positioned en el Cuartil Q3 for the agency WoS (JCR) in the category Rheumatology.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2025-12-21:

  • Google Scholar: 8
  • WoS: 5
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-12-21:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 55 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (MADRID GARCIA, ALFREDO) .

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Awards linked to the item

The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Instituto de Salud Carlos III (ISCIII), Ministry of Health, Spain (CPII17/00014; PI18/01188; CP16/00916; and RD16/0012/0014) and cofounded by el Fondo Europeo de Desarrollo Regional (FEDER). Funders had no role in the design, collection, management, analyses, interpretation of the data, preparation, review, approval or decision to submit the manuscript for publication.
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