September 10, 2018
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Review

Measuring quality of life among people living with HIV: a systematic review of reviews

Publicated to: Health And Quality Of Life Outcomes. 15 (1): 220- - 2017-11-15 15(1), DOI: 10.1186/s12955-017-0778-6

Authors:

Cooper, Vanessa; Clatworthy, Jane; Harding, Richard; Whetham, Jennifer;Emerge Consortium
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Affiliations

Brighton & Sussex Univ Hosp NHS Trust, Lawson Unit, Eastern Rd, Brighton BN2 1HS, E Sussex, England - Author
Grupo de Bioingeniería y Telemedicina. Universidad Politécnica de Madrid - Author
Kings Coll London, Fac Life Sci & Med, Cicely Saunders Inst, Dept Palliat Care Policy & Rehabil, Bessemer Rd, London SE5 9PJ, England - Author
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Abstract

Aim: A systematic review of reviews was conducted to identify and appraise brief measures of health-related quality of life (HRQoL) that have been used in peer-reviewed research with people living with HIV. Methods: The review was conducted in two stages: 1) search of electronic databases to identify systematic reviews of tools used to measure HRQoL in adults living with HIV, published since the year 2000; 2) selection of HRQol scales from those identified in the reviews. Inclusion criteria included scales that could be self-administered in 10 min or less, covering at least 3 domains of quality of life (physical function, social/role function and mental/emotional function). For generic scales, inclusion criteria included the availability of normative data while for HIV-specific scales, patient input into the development of the scale was required. Results: Ten reviews met the inclusion criteria. Nine generic scales met the inclusion criteria: the EuroQol five dimensions questionnaire (EQ-5D); Health Utilities Index; McGill Quality of Life questionnaire; Medical Outcomes Study (MOS) Short Form (SF)-12; SF-36; World Health Organisation Quality of Life (WHOQOL-BREF), Questions of Life Satisfaction (FLZM) and SF-20. Available psychometric data supported the EQ-5D and SF-36. Seven HIV-specific scales met the inclusion criteria: the AIDS Clinical Trials Group (ACTG)-21; HIV-QL-31; MOS-HIV; Multidimensional Quality of Life Questionnaire for Persons with HIV/AIDS (MQOL-HIV), PROQOL-HIV, Symptom Quality of Life Adherence (HIV-SQUAD) and the WHOQOL-HIV BREF. Of the HIV-specific measures, the MOS-HIV was considered to have the most well-established psychometric properties, however limitations identified in the reviews included insufficient input from people living with HIV in the development of the scale, cross-cultural relevance and continued applicability. Two relatively new measures, the WHOQOL-HIV BREF and PROQOL-HIV, were considered to have promising psychometric properties and may have more relevance to people living with HIV. Conclusion: The findings highlight the need for further validation of HRQoL measures in people living with HIV. The choice of one measure over another is likely to be influenced by the purpose of the quality of life assessment and the domains of HRQoL that are most relevant to the specific research or clinical question.
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Keywords

hivquality of lifereliabilitysystematic reviewBrefDiseaseForm health surveyHivHiv/aidsInfected patientsProqol-hivPsychometric validationQuality of lifeQuestionnaireReliabilitySurvey sf-36Systematic reviewValidity

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Health And Quality Of Life Outcomes due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2017, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Public Health, Environmental and Occupational Health.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations from Scopus Elsevier, it yields a value for the Field-Weighted Citation Impact from the Scopus agency: 5.23, which indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 13, 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-12-20, the following number of citations:

  • WoS: 84
  • Scopus: 149
  • Europe PMC: 43
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-12-20:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 517.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 520 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 2.
  • The number of mentions on the social network Facebook: 1 (Altmetric).
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: United Kingdom.

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Awards linked to the item

EmERGE is a project funded by the European Union's Horizon 2020 Research and Innovation Programme under Grant agreement no: 643736. The dissemination activities within the EmERGE project do not represent the opinion of the European Community and only reflect the opinion of the authors and / or the Consortium.
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