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September 15, 2022
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Synthetic biology open language visual (SBOL Visual) version 2.3

Publicated to:Journal Of Integrative Bioinformatics. 18 (3): - 2021-06-08 18(3), DOI: 10.1515/jib-2020-0045

Authors: Baig H; Fontanarossa P; Kulkarni V; McLaughlin J; Vaidyanathan P; Bartley B; Bhakta S; Bhatia S; Bissell M; Clancy K; Cox RS; Goñi Moreno A; Gorochowski T; Grunberg R; Lee J; Luna A; Madsen C; Misirli G; Nguyen T; Le Novere N; Palchick Z; Pocock M; Roehner N; Sauro H; Scott-Brown J; Sexton JT; Stan GB; Tabor JJ; Terry L; Vazquez Vilar M; Voigt CA; Wipat A; Zong D; Zundel Z; Beal J; Myers C

Affiliations

BBN Technologies - Author
Boston University - Author
Harvard Medical School - Author
Imperial College London - Author
Keele University - Author
King Abdullah University of Science and Technology - Author
Kobe University - Author
Massachusetts Institute of Technology - Author
Microsoft Research Cambridge - Author
Newcastle University - Author
Rice University - Author
Shipyard Toolchains LLC - Author
Technology Ltd - Author
The Babraham Institute - Author
The University of Utah - Author
Thermo Fisher Scientific Inc. - Author
Universitat Politècnica de València - Author
University of Bristol - Author
University of Colorado Boulder - Author
University of Connecticut - Author
University of Oxford - Author
University of Warwick - Author
University of Washington - Author
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Abstract

People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between sequence features and other molecular species. Some typical practices and conventions have begun to emerge for such diagrams. The Synthetic Biology Open Language Visual (SBOL Visual) has been developed as a standard for organizing and systematizing such conventions in order to produce a coherent language for expressing the structure and function of genetic designs. This document details version 2.3 of SBOL Visual, which builds on the prior SBOL Visual 2.2 in several ways. First, the specification now includes higher-level interactions with interactions, such as an inducer molecule stimulating a repression interaction. Second, binding with a nucleic acid backbone can be shown by overlapping glyphs, as with other molecular complexes. Finally, a new unspecified interaction glyph is added for visualizing interactions whose nature is unknown, the insulator glyph is deprecated in favor of a new inert DNA spacer glyph, and the polypeptide region glyph is recommended for showing 2A sequences.

Keywords

DiagramsSbol visualStandards

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Journal Of Integrative Bioinformatics due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2021, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Medicine (Miscellaneous).

From a relative perspective, and based on the normalized impact indicator calculated from the Field Citation Ratio (FCR) of the Dimensions source, it yields a value of: 1.26, which indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: Dimensions Nov 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-11-11, the following number of citations:

  • Scopus: 6

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-11-11:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 14 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Gran Bretanya; Japan; Saudi Arabia; United Kingdom; United States of America.